The Institut Sophia Agrobiotech (UMR Inra 1355, CNRS 7254, UNS), an international research institute funded by Inra, CNRS and Université Nice Sophia Antipolis. Situated at the interface of Environment and Agriculture, the main research topics concern the study of plant-interactions, pathogens and symbionts and their dynamics in time and space. For this, the Institute brings together strong expertise in comparative, evolutionary and functional genomics, in community ecology and agronomy. The institute aims to address some of the challenges offered for agricultural research in the field of ecological management of agroecosystems. The ultimate goal is to integrate this knowledge in the development of innovative agronomic strategies (integrated pest management, biological control), more respectful of the environment and human health.